Connect with us ! Google+ LinkedIn Pinterest YouTube

Vitamin D Benefits Questioned: Are We All Wrong About The Sunshine Vitamin?

Share on Facebook0Tweet about this on TwitterShare on LinkedIn19Share on Google+0Pin on Pinterest1Email this to someone

Vitamin D is one of the most widely accepted and rigorously researched natural substances. Numerous government and scientific agencies support vitamin D for health conditions such as bone vitaminhealth, cancer prevention and immune function. However, a recent meta-analysis suggests that the health links to vitamin D are weak and unconfirmed.1 Critics have already slammed the study on a number of points, calling into question its conclusions.2 Vitamin D is one of a few topics that conventional and alternative medicine can actually agree about since the evidence to date is overwhelmingly positive. Have we all been wrong about the benefits of vitamin D?

As with all new studies and reviews, this one also deserves a closer look to confirm the conclusions.

1) Beware of shock and awe titles: The conclusion of the aforementioned study states that “highly convincing evidence of a clear role of vitamin D does not exist for any outcome, but associations with a selection of outcomes are probable.” This seems like a cautious and conservative statement which is no surprise considering the type of review it is, and also the nature of vitamin D testing and supplementation (keep reading below for details). However sensationalist titles like “Vitamin D Supplements Don’t Help Your Health” ( from wedMD) don’t accurately reflect the details of the paper.3

2) The most recent study was a meta-analysis of systematic reviews and meta-analyses. This approach is problematic for making meaningful conclusions from the results because the broad and general viewpoint loses any of the important details of each study. A good analogy is zooming out while looking at google maps in order to get a better overall view; but when you zoom too far you lose any meaningful details. Meta analysis and systematic reviews are already a “zoomed out” perspective, which tend to have vague and conservative conclusions. It is little surprise that this vitamin D review found no positive associations.

3) Another risk of a meta-analysis is that there is bias in terms of the studies that were selected. The reviews that were selected to be included in the meta-analysis were subjective and therefore open to bias. This means some studies with positive results may not have been included, and some reviews with flawed methods were included. Even one of the authors of the paper stated the large meta-analyses are ‘subjective and suboptimal.’

4) Another recent meta-analysis on Vitamin D and specific causes of death found that observational studies show that higher vitamin D levels were associated with a lower risk of death from cancer, heart disease and other conditions.4 However, randomized controlled trials found no association.4 This highlights the difficulties and variation that all vitamin D trials are subject to:

  1. The dose of vitamin D is usually too low. If you are already deficient, then 1000 IU (Health Canada’s daily limit) will do little to bring you up to protective levels. A higher dose is needed to rapidly restore levels while a lower dose is adequate for maintenance.
  2. Most people don’t remember to take vitamin D on a daily basis. Some studies have shown that high doses (10,000 – 50,000 IU per week) are better to build levels and people have an easier time remembering to take less frequent doses. 5,6
  3. Measuring vitamin D levels in the blood is notoriously inaccurate. There most likely is a wide variability in the testing used in the studies included in the meta-analysis. Even the standard testing for 25-OH vitamin D has wide margins of error in lab analysis.
  4. Vitamin D is fat soluble, meaning it should be taken in an oil base and with a meal. Without this, people may not be absorbing the vitamin D they are supplementing orally. Additionally, some people may not be able to digest and absorb fats if they have poor lipase and gallbladder function.

There is an overwhelming amount of positive evidence that adequate vitamin D levels are protective for a wide variety of health issues. In my opinion, this review does not present any compelling facts to stop using vitamin D. It does highlight that we always need more research to better understand this complex neuro-hormone. We need to find more accurate testing methods and efficient supplementations strategies. To get the most out your vitamin D use consider the following:

  1. Look for an oil based vitamin D supplement. Take it with meals containing a fat since this will increase the secretion of bile to help absorb fats.
  2. Use vitamin D3 over D2 since it’s the active form used the body.
  3. Get daily exposure to natural sunlight in the summer months.
  4. Get your 25-OH vitamin D levels tested. It’s the only way to guide you to your optimal dose. If you are deficient, then consider taking a high dose under the supervision of a licensed practitioner that can follow your calcium levels. Don’t just supplement with high doses without testing first. There is a real risk of developing excess calcium levels.

Image by © 2013 Blanche via DollarPhotoClub

References

1) Theodoratou E1, Tzoulaki I, Zgaga L, Ioannidis JP. Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ. 2014 Apr 1;348:g2035. doi: 10.1136/bmj.g2035.

2) http://www.nutraingredients.com/Research/BMJ-vitamin-D-research-attacked-un-nuanced-flawed-irresponsible/?utm_source=newsletter_daily&utm_medium=email&utm_campaign=Newsletter%2BDaily&c=zJaX8RDnc%2B65z599DRJwiP7uqhh5AzMb

3)  http://www.webmd.com/vitamins-and-supplements/news/20140124/vitamin-d-supplements-dont-help-your-health-review

4) Chowdhury et al.  Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ. 2014 Apr 1;348:g1903. doi: 10.1136/bmj.g1903.

5) Havens et al.  Serum 25-hydroxyvitamin D response to vitamin D3 supplementation 50,000 IU monthly in youth with HIV-1 infection. J Clin Endocrinol Metab. 2012 Nov;97(11):4004-13. doi: 10.1210/jc.2012-2600. Epub 2012 Aug 29.

6) Middleton et al. Vitamin D deficiency: A simple algorithm employing weekly administration of 50,000IU of vitamin D. Am J Otolaryngol. 2014 Mar-Apr;35(2):85-8. doi: 10.1016/j.amjoto.2013.12.002. Epub 2013 Dec 12.

Leave a Reply

Your email address will not be published. Required fields are marked *

Retype the CAPTCHA code from the image
Change the CAPTCHA codeSpeak the CAPTCHA code
 

Protected with IP Blacklist CloudIP Blacklist Cloud

JOIN US NOW
Purus sed vel ultricies, lorem rhoncus. Augue hac, adipiscing risus, sed ac? Pid nunc dignissim, non, ac parturient sociis enim.
Your Information will never be shared with any third party.
SUBSCRIBE TO NEWSLETTER
All rights reserved © Company Name, 2014
Dolor aliquet augue augue sit magnis, magna aenean aenean et! Et tempor, facilisis cursus turpis tempor odio, cursus montes ac turpis. Ultrices! Massa integer augue ridiculus adipiscing, massa cras pid. Turpis placerat scelerisque, vut odio mus non, mattis porttitor, nunc odio, turpis tortor sit? Pid amet, sed facilisis.
  • Goblinus globalus fantumo tandempo
  • Scelerisque cursus dignissim donus
  • Montes vutario lacus quis arcupolisio
  • Leftomato denitro oculus tepircos den
  • Spiratio dodenus christmas popupius
  • Afrenius globalus spiritum tandempo
  • Fitatos vutario lacus quis arcup delis
Here's $3 Off
Apply $3 off at checkout to any AOR product purchase. Just send your name and email and we'll email you your coupon.
Your Information will never be shared with any third party.
JOIN US NOW
Stay ahead of the curve with the latest AOR news, industry trends, and new product launches.
Your Information will never be shared with any third party.
Do you want massive traffic?
Dignissim enim porta aliquam nisi pellentesque. Pulvinar rhoncus magnis turpis sit odio pid pulvinar mattis integer aliquam!
  • Goblinus globalus fantumo tubus dia montes
  • Scelerisque cursus dignissim lopatico vutario
  • Montes vutario lacus quis preambul den lacus
  • Leftomato denitro oculus softam lorum quis
  • Spiratio dodenus christmas gulleria tix digit
  • Dualo fitemus lacus quis preambul pat turtulis
* we never share your e-mail with third parties.
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
COMPANY UPDATES
INDUSTRY TRENDS
PRODUCT LAUNCHES
Nutrition Education
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
Science-based facts from our team of top medical experts delivered right to your inbox!
Health Basics
Fitness Advice
JOIGNEZ-NOUS AUJOURD'HUI
Les dernières nouvelles:
AOR s’engage à protéger la confidentialité de vos données. Elles ne seront pas partagées avec des tiers. Vous pouvez vous désabonner à tout moment
MISE À JOUR
TENDANCES DE L'INDUSTRIE
LANCEMENTS DE PRODUITS
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
SPECIAL RETAILER OFFERS
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
MONTHLY PRICE LIST
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
PRODUCT LAUNCHES