Connect with us ! Google+ LinkedIn Pinterest YouTube

Curcumin and its Role in Potentially Preventing Alzheimer’s Disease

Share on Facebook0Tweet about this on TwitterShare on LinkedIn0Share on Google+0Pin on Pinterest0Email this to someone

Alzheimer’s disease is the most common form of dementia.  Named after the German doctor who first described the condition, Alois Alzheimer, it is a progressive disease during which proteins build up and form “plaques” in the brain.  Plaque development causes cell death resulting in neural signaling disruption, and a reduction in the development of neurotransmitters.

Initially, patients may present with more mild symptoms, such as slight memory lapses. Later as more neurons in the hippocampus begin to die, patients may experience more severe memory impairment, which can affect daily life. Patients may go on to have difficulty with language, concentration, orientation and may begin to suffer from anxiety and depression. In the later stages patients will need more day-to-day support and will often experience difficulties eating or walking without help.

Turmeric root with bowl of powder on white cloth background

The disease predominately affects people over the age of 65, and affects women more commonly than men.  In 2016, it was estimated that there were 564,000 Canadians living with dementia, approximately 14% of the population over the age of 65. By 2030, these numbers are expected to rise to over 900,000. The cost of Alzheimer’s disease is staggering with healthcare and social care costs estimated to be $10.4 billion annually.

Despite heavy investment into Alzheimer’s disease research, the exact cause of the disease remains unknown. Currently there is no cure for the disease, though there are drugs on the market that can help alleviate some of the symptoms.  Risk factors include age, gender, BMI and cardiovascular disease.

Some research has suggested that the overexpression of proinflammatory cytokines contributes to plaque formation and subsequent neuronal death. Proinflammatory cytokines are produced by support cells in the brain called microglial cells.

Curcumin (turmeric), is a herb commonly used in East Asian curry powder.  Due to its antioxidant properties, curcumin has been used extensively to treat a plethora of medical conditions including heart disease, arthritis and liver diseases. It has been suggested that curcumin may aid in the prevention and potential treatment in Alzheimer’s disease.  Studies have shown that curcumin blocks NF-kB a signaling molecule that leads to the production of proinflammatory cytokines. A study conducted at UCLA medical center showed that curcumin aids macrophages (immune cells) in clearing amyloid plaques. The macrophages from Alzheimer’s patients treated with curcumin showed increased uptake and ingestion of plaques  compared to the macrophages from patients that were not given curcumin supplementation. By reducing inflammation and by promoting plaque destruction, curcumin may have a potential role in curing the disease. anxiety-man

Whilst there have only been a few human clinical trials with small sample sizes looking at the effects of curcumin in Alzheimer’s, various epidemiological studies have shown that there is a lower incidence of Alzheimer’s in East Asian countries, where curcumin is consumed on a daily basis. Interestingly, researchers found that individuals who consumed curcumin more regularly preformed better on cognitive tests than those who only occasionally consumed curcumin. Finally, high fat diets and high blood cholesterol levels are both risk factors in the development of Alzheimer’s. Curcumin has been shown to reduce cholesterol formation, which may in turn reduce the risk of developing Alzheimer’s.

Although the main chemical property that can be used in the treatment of Alzheimer’s has not been determined, curcumin remains a promising preventative supplement for this devastating disease.

For more information on the range of curcumin products availably by AOR, please visit:  http://www.aor.ca/en/home

 

Leave a Reply

Your email address will not be published. Required fields are marked *

Retype the CAPTCHA code from the image
Change the CAPTCHA codeSpeak the CAPTCHA code
 

Protected with IP Blacklist CloudIP Blacklist Cloud

JOIN US NOW
Purus sed vel ultricies, lorem rhoncus. Augue hac, adipiscing risus, sed ac? Pid nunc dignissim, non, ac parturient sociis enim.
Your Information will never be shared with any third party.
SUBSCRIBE TO NEWSLETTER
All rights reserved © Company Name, 2014
Dolor aliquet augue augue sit magnis, magna aenean aenean et! Et tempor, facilisis cursus turpis tempor odio, cursus montes ac turpis. Ultrices! Massa integer augue ridiculus adipiscing, massa cras pid. Turpis placerat scelerisque, vut odio mus non, mattis porttitor, nunc odio, turpis tortor sit? Pid amet, sed facilisis.
  • Goblinus globalus fantumo tandempo
  • Scelerisque cursus dignissim donus
  • Montes vutario lacus quis arcupolisio
  • Leftomato denitro oculus tepircos den
  • Spiratio dodenus christmas popupius
  • Afrenius globalus spiritum tandempo
  • Fitatos vutario lacus quis arcup delis
Here's $3 Off
Apply $3 off at checkout to any AOR product purchase. Just send your name and email and we'll email you your coupon.
Your Information will never be shared with any third party.
JOIN US NOW
Stay ahead of the curve with the latest AOR news, industry trends, and new product launches.
Your Information will never be shared with any third party.
Do you want massive traffic?
Dignissim enim porta aliquam nisi pellentesque. Pulvinar rhoncus magnis turpis sit odio pid pulvinar mattis integer aliquam!
  • Goblinus globalus fantumo tubus dia montes
  • Scelerisque cursus dignissim lopatico vutario
  • Montes vutario lacus quis preambul den lacus
  • Leftomato denitro oculus softam lorum quis
  • Spiratio dodenus christmas gulleria tix digit
  • Dualo fitemus lacus quis preambul pat turtulis
* we never share your e-mail with third parties.
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
COMPANY UPDATES
INDUSTRY TRENDS
PRODUCT LAUNCHES
Nutrition Education
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
Science-based facts from our team of top medical experts delivered right to your inbox!
Health Basics
Fitness Advice
JOIGNEZ-NOUS AUJOURD'HUI
Les dernières nouvelles:
AOR s’engage à protéger la confidentialité de vos données. Elles ne seront pas partagées avec des tiers. Vous pouvez vous désabonner à tout moment
MISE À JOUR
TENDANCES DE L'INDUSTRIE
LANCEMENTS DE PRODUITS
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
SPECIAL RETAILER OFFERS
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
MONTHLY PRICE LIST
JOIN US TODAY
For the latest:
AOR is committed to your privacy, your information will not be shared with any third party. You may unsubscribe at any time.
PRODUCT LAUNCHES